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Abamectin is generally considered safe for humans when used according to the manufacturer's instructions. However, it can be toxic if ingested or if it comes into contact with the skin or eyes.

Abamectin is broken down by sunlight and microorganisms in the soil, so it generally does not persist in the environment for very long. However, it can accumulate in the tissues of certain organisms if they are exposed to it over a long period of time.

Abamectin is labeled for use on a wide range of crops, including fruits, vegetables, and ornamental plants. However, it is important to read the label carefully to ensure that the specific crop and pest are listed before applying.

Abamectin is not approved for use in organic farming, as it is a synthetic chemical. However, it is approved for use in some integrated pest management (IPM) programs.

Abamectin can be harmful to some beneficial insects, such as bees and predatory mites. It is important to read the label carefully and use the product only as directed to minimize the impact on non-target organisms.